Global Availability Of
Botulinum Toxin Products

2025abotulinum_toxin_global_snapshot_updated_edited.jpg

12/22/2025

*See text version of the chart below.

There is currently no centralized or authoritative public database that accurately documents where each botulinum toxin product is approved or marketed across countries. Information is fragmented across manufacturer communications, regulatory agencies, press releases, and country specific approval records, and is often incomplete, outdated, or presented in non-standardized ways.

To address this gap, our team conducted a months-long review of primary source materials, including manufacturer disclosures, regulatory authority publications, approval summaries, and publicly available government records. Each data point was individually reviewed and cross-checked to ensure accuracy at the time of publication.

This chart reflects regulatory approval or documented market availability only. It does not compare safety, efficacy, quality, dosing, or clinical interchangeability. Approval status does not imply equivalence across products or indications, and regulatory frameworks vary significantly by country and region. In some cases it's "TRUE" status reflects product registration/use rather than full approval.

For clarity and accessibility, the data has been simplified for visual presentation on our Instagram slides, @nevertox The Dark Side of Tox.

Text version:

Products Approved in the United States (“US”)

Botox (onabotulinumtoxinA) — AbbVie / Allergan

Available in:
United States, UK/EU, Australia, Argentina, Brazil, Canada, Chile, China, Egypt, Germany, India, Indonesia, Iran, Japan, Mexico, Philippines, Russia, Saudi Arabia / UAE, South Africa, South Korea, Thailand, Turkey

Dysport / Azzalure (abobotulinumtoxinA) — Ipsen / Galderma

Xeomin / Bocouture (incobotulinumtoxinA) — Merz

Jeuveau / Nuceiva (prabotulinumtoxinA) — Evolus / Daewoong

Available in:
United States, UK/EU, Australia, Argentina, Canada, Chile, Egypt, Germany, Indonesia, Japan, Mexico, Philippines, South Korea, Thailand, Turkey

Not available in:
Brazil, China, India, Iran, Russia, Saudi Arabia / UAE, South Africa

Note: Japan availability is listed as a biosimilar.

Daxxify (daxibotulinumtoxinA) — Revance

Available in:
United States

Not available in:
UK/EU, Australia, Argentina, Brazil, Canada, Chile, China, Egypt, Germany, India, Indonesia, Iran, Japan, Mexico, Philippines, Russia, Saudi Arabia / UAE, South Africa, South Korea, Thailand, Turkey

Letybo (letibotulinumtoxinA) — Hugel / Croma

Available in:
United States, UK/EU, Australia, Brazil, Canada, Germany, Indonesia, Iran, Japan, Russia, South Korea, Thailand, Turkey

Not available in:
Argentina, Chile, China, Egypt, India, Mexico, Philippines, Saudi Arabia / UAE, South Africa

Products NOT Approved in the United States (“Not US”)

Nabota (prabotulinumtoxinA) — Daewoong

Available in:
Brazil, Chile, China, Egypt, Germany, Indonesia, Japan, Philippines, Russia, Saudi Arabia / UAE, South Korea, Thailand, Turkey

Not available in:
United States, UK/EU, Australia, Argentina, Canada, India, Iran, Mexico, South Africa

Botulax (BoNT-A) — Hugel

Available in:
Brazil, Chile, China, Germany, Indonesia, Iran, Japan, Philippines, Russia, Saudi Arabia / UAE, South Korea, Turkey

Not available in:
United States, UK/EU, Australia, Argentina, Canada, Egypt, India, Mexico, South Africa, Thailand

Innotox (liquid BoNT-A) — Medytox

Available in:
China, Germany, Russia, South Korea, Thailand

Not available in:
United States, UK/EU, Australia, Argentina, Brazil, Canada, Chile, Egypt, India, Indonesia, Iran, Japan, Mexico, Philippines, Saudi Arabia / UAE, South Africa, Turkey

Neuronox / Meditoxin — Medytox

Available in:
China, Egypt, Indonesia, Iran, Japan, Philippines, Russia, South Korea, Thailand, Turkey

Not available in:
United States, UK/EU, Australia, Argentina, Brazil, Canada, Chile, Germany, India, Mexico, Saudi Arabia / UAE, South Africa

Prosigne / Lantox (onabotulinumtoxinA) — Lanzhou Institute (China)

Available in:
Brazil, China, Indonesia, Iran*, Russia, South Korea

Not available in:
United States, UK/EU, Australia, Argentina, Canada, Chile, Egypt, Germany, India, Japan, Mexico, Philippines, Saudi Arabia / UAE, South Africa, Thailand, Turkey

Note: Iran availability marked with special regulatory status.

Data Sources

Information was gathered from multiple source types, including:

Manufacturer and distributor websites
Official regulatory authority publications and approval databases
Government drug registries
Press releases and investor communications referencing regulatory milestones
Publicly available country-specific regulatory notices
Where possible, primary sources were prioritized over secondary reporting

Verification Process

Each product–country pairing was evaluated individually. Availability was only marked as “TRUE” when there was evidence of one or more of the following:

- Formal regulatory approval

- Legal market authorization

- Documented distribution or licensed commercialization

- Conflicting or ambiguous claims were resolved by cross-referencing multiple independent sources. In cases where definitive confirmation could not be established, availability was marked as “FALSE.”

Definitions and Limitations

“Availability” refers to regulatory approval or lawful market presence within a country. It does not imply:

- Approved clinical indications

- Interchangeability between products

- Safety or efficacy comparisons

- Scope of use or dosing equivalence

- Regulatory frameworks differ substantially between countries, and approval pathways may include full approvals, conditional authorizations, or region-specific classifications. Some products may be marketed under different brand names or regulatory designations in certain regions, including biosimilar or locally licensed formulations.

Currency of Data

This dataset reflects the most current information available at the time of compilation, December 2025. Regulatory status may change as approvals are granted, withdrawn, or modified. Periodic review and updates are planned as new information becomes available.

*This compilation is the original work of Tox Safety/Never Tox and is provided for educational and informational purposes. To avoid DMCA violation, reproduction or redistribution should include clear attribution to us, the original source. Please contact us for written permission.

Global Availability Of Botulinum Toxin Products

Join the Tox Safety mailing list.

Global Availability Of
Botulinum Toxin Products